Cardura XL and Gilteritinib Fumarate

• Generic Name: doxazosin
• Dosage Forms: tablet, multilayer, extended release
• Other Brand Names: Cardura, Cardura XL, Doxadura, Cascor, Carduran

Cardura XL is an alpha-adrenergic (AL-fa ad-ren-ER-jik) blockers. This medicine relaxes your veins and arteries so that blood can more easily pass through them. It also relaxes the muscles in the prostate and bladder neck, making it easier to urinate.

Cardura XL is used to treat hypertension (high blood pressure), or to improve urination in men with benign prostatic hyperplasia (enlarged prostate).

The extended-release form of doxazosin (Cardura XL) is for use only in treating benign prostatic hyperplasia and should not be used to treat hypertension.

Cardura XL may also be used for purposes not listed in this medication guide.

• Generic Name: gilteritinib
• Dosage Forms: n.a.
• Other Brand Names: Xospata

For the treatment of relapsed or refractory AML harboring Flt-3 mutation (designated an orphan drug by FDA for this use).

FDA-approved companion diagnostic test (e.g., LeukoStrat CDx Flt-3 mutation assay) required to confirm presence of Flt-3 mutation prior to initiation of therapy.