Carvedilol Extended-Release Capsules and Fluconazole in Dextrose Injection
Determining the interaction of Carvedilol Extended-Release Capsules and Fluconazole in Dextrose Injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using carvedilol together with fluconazole may increase the effects of carvedilol. Contact your doctor if you experience slow heartbeat, low blood pressure, swelling, headaches, dizziness, or feeling like you might pass out. You may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Fluconazole may increase serum levels of carvedilol. The mechanism is inhibition of CYP450 2C9, one of the isoenzymes involved in the metabolism of carvedilol. Further reductions in heart rate or cardiac conduction may occur.
MANAGEMENT: Patients should be monitored for signs of increased carvedilol effects, such as bradycardia or heart block.
- "Product Information. Coreg (carvedilol)." SmithKline Beecham, Philadelphia, PA.
Generic Name: carvedilol
Brand name: Coreg, Coreg CR
Synonyms: Carvedilol
Generic Name: fluconazole
Brand name: Diflucan
Synonyms: Fluconazole
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Carvedilol Extended-Release Capsules-Fluconazole Injection
- Carvedilol Extended-Release Capsules-Fluconazole Injection Solution
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- Carvedilol Extended-Release Capsules-Fluconazole Oral Suspension
- Carvedilol Extended-Release Capsules-Fluconazole Tablets
- Carvedilol Extended-Release Capsules-Flucytosine
- Fluconazole in Dextrose Injection-Carvedilol Tablets
- Fluconazole in Dextrose Injection-Cascara
- Fluconazole in Dextrose Injection-Casodex
- Fluconazole in Dextrose Injection-Caspofungin
- Fluconazole in Dextrose Injection-Caspofungin Acetate
- Fluconazole in Dextrose Injection-Caspofungin Acetate Injection