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Cataflam and Cholestyramine

Determining the interaction of Cataflam and Cholestyramine and the possibility of their joint administration.

Check result:
Cataflam <> Cholestyramine
Relevance: 14.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Coadministration of cholestyramine and diclofenac significantly reduces the bioavailability of diclofenac. The clinical significance of this reduction is not clear. Separating the administration of diclofenac and cholestyramine doses may diminish the effects of this interaction.

References
  • Alballa SR, Elsayed YM, Almeshal MA, Gouda MW "The effects of cholestyramine and colestipol on the absorption of diclofenac in man." Int J Clin Pharmacol Ther 32 (1994): 441-5
Cataflam

Generic Name: diclofenac

Brand name: Cataflam, Zipsor, Zorvolex, Voltaren, Cambia, Voltaren-XR, Dyloject, also Cambia

Synonyms: n.a.

Cholestyramine

Generic Name: cholestyramine

Brand name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: Cholestyramine Resin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction