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Catapres and Nitroprusside

Determining the interaction of Catapres and Nitroprusside and the possibility of their joint administration.

Check result:

Catapres <> Nitroprusside

Relevance: 18.05.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using cloNIDine together with sodium nitroprusside may result in a severe decrease in blood pressure. This can cause dizziness or feeling like you might pass out, especially when getting up from a sitting or lying position. If your doctor prescribes these medications together, you may need a dose adjustment or need your blood pressure checked more often to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: The concurrent administration of some centrally acting alpha-agonists and nitroprusside may result in severe hypotension. The proposed mechanism is additive pharmacodynamic effects.

MANAGEMENT: Management consists of carefully monitoring hemodynamics during coadministration and titrating the dosage of nitroprusside as necessary.

References

"Product Information. Nipride (nitroprusside)." Roche Laboratories, Nutley, NJ.
Cohen IM, Mottet MM, Francis GS, Alpert JS "Danger in nitroprusside therapy." Ann Intern Med 85 (1976): 205-6

Catapres

Generic Name: clonidine

Brand name: Catapres, Catapres-TTS, Duraclon, Kapvay, Catapres-TTS-1, Catapres-TTS-2, Catapres-TTS-3

Synonyms: n.a.

What is Catapres?

Nitroprusside

Generic Name: nitroprusside

Brand name: Nitropress, Nipride RTU

Synonyms: n.a.

What is Nitroprusside?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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