Cathflo Activase and Ismelin

• Generic Name: alteplase
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Activase, Cathflo Activase

Cathflo Activase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots.

Cathflo Activase is used to treat a stroke caused by a blood clot or other obstruction in a blood vessel. This medicine is also used to prevent death from a heart attack (acute myocardial infarction).

Cathflo Activase is also used to treat a blood clot in the lung (pulmonary embolism).

Cathflo Activase is also used to dissolve blood clots that have formed in or around a catheter placed inside a blood vessel. This improve the flow of medicines injected in through the catheter, or blood drawn out through the catheter.

Cathflo Activase may also be used for purposes not listed in this medication guide.

• Generic Name: guanethidine
• Dosage Forms: Tablets
• Other Brand Names:

Guanethidine belongs to the general class of medicines called antihypertensives. It is used to treat high blood pressure (hypertension).

High blood pressure adds to the work load of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Guanethidine works by controlling nerve impulses along certain nerve pathways. As a result, it relaxes the blood vessels so that blood passes through them more easily. This helps to lower blood pressure.

Guanethidine is available only with your doctor's prescription.