Cathflo Activase and Zelboraf

• Generic Name: alteplase
• Dosage Forms: injection, powder, lyophilized, for solution
• Other Brand Names: Activase, Cathflo Activase

Cathflo Activase is a thrombolytic (THROM-bo-LIT-ik) drug, sometimes called a "clot-busting" drug. It helps your body produce a substance that dissolves unwanted blood clots.

Cathflo Activase is used to treat a stroke caused by a blood clot or other obstruction in a blood vessel. This medicine is also used to prevent death from a heart attack (acute myocardial infarction).

Cathflo Activase is also used to treat a blood clot in the lung (pulmonary embolism).

Cathflo Activase is also used to dissolve blood clots that have formed in or around a catheter placed inside a blood vessel. This improve the flow of medicines injected in through the catheter, or blood drawn out through the catheter.

Cathflo Activase may also be used for purposes not listed in this medication guide.

• Generic Name: vemurafenib
• Dosage Forms: tablet, film coated
• Other Brand Names: Zelboraf

Zelboraf (vemurafenib) is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Zelboraf is used to treat melanoma (skin cancer) that has spread to other parts of the body or cannot be removed by surgery.

Zelboraf is also used to treat Erdheim-Chester Disease (a rare blood cancer).

Zelboraf is used only if your cancer has a specific genetic marker (an abnormal "BRAF" gene). Your doctor will test you for this gene.