Cefditoren and Sodium Bicarbonate Infant Injection

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Ask your doctor before using sodium bicarbonate together with cefditoren. Medications that reduce stomach acid such as sodium bicarbonate can cause cefditoren to be less effective. You should generally avoid using sodium bicarbonate while taking cefditoren. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

GENERALLY AVOID: Coadministration with antacids or agents with acid-neutralizing effects may reduce the oral absorption and plasma concentrations of cefditoren pivoxil. According to the manufacturer, a dose of an antacid containing magnesium hydroxide (800 mg) and aluminum hydroxide (900 mg) reduced the mean peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of a single dose of cefditoren pivoxil (400 mg, administered following a meal) by 14% and 11%, respectively. The clinical significance of these alterations is unknown.

MANAGEMENT: The manufacturer recommends that cefditoren pivoxil not be administered concomitantly with antacids or oral medications that contain antacids (e.g., didanosine buffered tablets or pediatric oral solution).

Cefditoren

Generic Name: cefditoren

Brand name: Spectracef

Synonyms: n.a.

What is Cefditoren?

Sodium Bicarbonate Infant Injection

Generic Name: sodium bicarbonate

Brand name: Neut

Synonyms: Sodium bicarbonate, Sodium Bicarbonate

What is Sodium Bicarbonate Infant Injection?