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Cefixime Oral Suspension and Procardia

Determining the interaction of Cefixime Oral Suspension and Procardia and the possibility of their joint administration.

Check result:
Cefixime Oral Suspension <> Procardia
Relevance: 28.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Nifedipine may increase the bioavailability of cefixime. The mechanism appears to be nifedipine enhancement of cefixime absorption. This interaction appears to be clinically insignificant.

References
  • Duverne C, Bouten A, Deslandes A "Modification of cefixime bioavailabity by nifedipine in humans: involvement of the dipeptide carrier system." Antimicrob Agents Chemother 36 (1992): 2462-7
Cefixime Oral Suspension

Generic Name: cefixime

Brand name: Suprax

Synonyms: Cefixime

Procardia

Generic Name: nifedipine

Brand name: Adalat CC, Procardia, Procardia XL, Afeditab CR, Nifediac CC, Nifedical XL, Adalat

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction