Ceftriaxone and Neoral

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using cycloSPORINE together with cefTRIAXone can increase the effects of cycloSPORINE and cause damage to the kidneys or cause nerve loss. Tell your doctor if you experience dizziness, numbness, skin tingling, muscle twitching, or seizures which may be signs of nerve damage. Talk with your doctor if you develop fever, chills, body aches, flu symptoms, and severe pain in your upper stomach spreading to your back. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Limited data suggest that ceftriaxone may increase cyclosporine serum concentrations. Risk of cyclosporine-induced neurotoxicity and nephrotoxicity may be increased. The mechanism is unknown.

MANAGEMENT: If cyclosporine and ceftriaxone are used together, cyclosporine levels and renal function, including serum creatinine, should be carefully monitored. Cyclosporine dosage should be adjusted as needed. Patients should be advised to notify their physician if they experience nausea, vomiting, diarrhea, abdominal pain, dizziness, fatigue, or headache.

Ceftriaxone

Generic Name: ceftriaxone

Brand name: Rocephin, Rocephin IM Convenience Kit, Rocephin ADD-Vantage

Synonyms: Ceftriaxone (injection), CefTRIAXone

What is Ceftriaxone?

Neoral

Generic Name: cyclosporine

Brand name: Gengraf, Neoral, Sandimmune, Sandimmune

Synonyms: Neoral (Capsules, Modified)

What is Neoral?