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Ceftriaxone and Zipsor

Determining the interaction of Ceftriaxone and Zipsor and the possibility of their joint administration.

Check result:

Ceftriaxone <> Zipsor

Relevance: 06.02.2023 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Diclofenac increases biliary excretion and decreases renal elimination of ceftriaxone in patients with bile duct drains. The mechanism and the clinical significance of this interaction are unknown.

References

Merle-Melet M, Bresler L, Lokiec F, et al "Effects of diclofenac on ceftriaxone pharmacokinetics in humans." Antimicrob Agents Chemother 36 (1992): 2331-3

Ceftriaxone

Generic Name: ceftriaxone

Brand name: Rocephin, Rocephin IM Convenience Kit, Rocephin ADD-Vantage

Synonyms: Ceftriaxone (injection), CefTRIAXone

What is Ceftriaxone?

Zipsor

Generic Name: diclofenac

Brand name: Zipsor, Cambia, Cataflam, Zorvolex, Voltaren, Voltaren-XR, Dyloject, also Cambia

Synonyms: n.a.

What is Zipsor?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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