Celecoxib and Delavirdine

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Theoretically, celecoxib may inhibit the CYP450 2D6 metabolism of delavirdine, and delavirdine may inhibit the CYP450 2C9 metabolism of celecoxib. The clinical significance of this interaction is unknown. Patients who are poor metabolizers of CYP450 2C9 may be at a greater risk of developing high celecoxib plasma levels. Patients should be observed for altered effects of both celecoxib and delavirdine. Dose adjustments may be required if an interaction is suspected.

Celecoxib

Generic Name: celecoxib

Brand name: Celebrex, Celebrex

Synonyms: n.a.

What is Celecoxib?

Delavirdine

Generic Name: delavirdine

Brand name: Rescriptor

Synonyms: n.a.

What is Delavirdine?