Celestone Soluspan injection and Magnesium Oxide 400
Determining the interaction of Celestone Soluspan injection and Magnesium Oxide 400 and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Antacids and agents with acid-neutralizing effects may impair the absorption of dexamethasone, prednisolone, prednisone, and other corticosteroids, although data from published studies are somewhat conflicting. The mechanism of interaction and clinical significance are unknown. No particular intervention is necessary during concomitant therapy with these agents, but clinicians should be aware of the potential for interaction.
- Naggar VF, Khalil SA, Gouda MW "Effect of concomitant administration of magnesium trisilicate on GI absorption of dexamethasone in humans." J Pharm Sci 67 (1978): 1029-30
- Tanner AR, Caffin JA, Halliday JW, Powell LW "Concurrent administration of antacids and prednisone: effect on serum levels of prednisolone." Br J Clin Pharmacol 7 (1979): 397-400
- Albin H, Vincon G, Demotes-Mainard F, et al "Effect of aluminium phosphate on the bioavailability of cimetidine and prednisolone." Eur J Clin Pharmacol 26 (1984): 271-3
Generic Name: betamethasone
Brand name: Celestone Soluspan, Celestone, Celestone Phosphate, Selestoject, Cell-U-Jec, Adbeon, Beta-Phos/AC
Synonyms: Celestone Soluspan (injection), Celestone Soluspan
Generic Name: magnesium oxide
Brand name: MagGel, Phillips' Cramp-free, Uro-Mag, Mag-200, Mag-Ox 400, UroMag, Mag-Oxide, Magnesium Oxide 400, MAGnesium-Oxide, Maox, Uro-Mag
Synonyms: Magnesium oxide, Magnesium Oxide
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Celestone Soluspan injection-Magnesium salicylate
- Celestone Soluspan injection-Magnesium sulfate
- Celestone Soluspan injection-Magnesium Sulfate Granules (Epsom Salt)
- Celestone Soluspan injection-Magnesium Sulfate in Dextrose Injection
- Celestone Soluspan injection-Magnesium sulfate injection
- Celestone Soluspan injection-Magnesium sulfate Oral, Topical application, Route Not Applicable
- Magnesium Oxide 400-Celexa
- Magnesium Oxide 400-Celexa (Citalopram Solution)
- Magnesium Oxide 400-Celexa (Citalopram Tablets)
- Magnesium Oxide 400-Celexib 100- EZS
- Magnesium Oxide 400-Cellcept
- Magnesium Oxide 400-CellCept (Mycophenolate Mofetil Capsules)