Celexib 100- EZS and Extendryl HC
Determining the interaction of Celexib 100- EZS and Extendryl HC and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Celecoxib may increase the blood levels and effects of HYDROcodone. If your doctor does prescribe these medications together, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or if your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with celecoxib may increase the plasma concentrations of drugs that are substrates of the CYP450 2D6 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by celecoxib.
MANAGEMENT: Caution is advised if celecoxib must be used concurrently with medications that undergo metabolism by CYP450 2D6, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever celecoxib is added to or withdrawn from therapy.
- "Product Information. Celebrex (celecoxib)." Searle, Chicago, IL.
Generic Name: celecoxib
Brand name: Celebrex, Celebrex
Synonyms: Celecoxib
Generic Name: guaifenesin / hydrocodone
Brand name: Xtrelus
Synonyms: Extendryl HC (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Celexib 100- EZS-Extra-Virt Plus DHA
- Celexib 100- EZS-Exubera
- Celexib 100- EZS-Eye Allergy Relief
- Celexib 100- EZS-Eye Cool
- Celexib 100- EZS-Eye Drops
- Celexib 100- EZS-EZ Gas II
- Extendryl HC-Cellcept
- Extendryl HC-CellCept (Mycophenolate Mofetil Capsules)
- Extendryl HC-CellCept (Mycophenolate Mofetil Injection Solution)
- Extendryl HC-CellCept (Mycophenolate Mofetil Oral Suspension)
- Extendryl HC-CellCept (Mycophenolate Mofetil Tablets)
- Extendryl HC-Cellcept Oral