Celexib 100- EZS and Fluvoxamine Extended-Release Capsules
Determining the interaction of Celexib 100- EZS and Fluvoxamine Extended-Release Capsules and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using fluvoxaMINE together with celecoxib can increase the effects of celecoxib. This can cause abdominal pain, tarry stools, nausea, vomiting, lethargy or drowsiness. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment if you take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inhibitors of CYP450 2C9 may increase the plasma concentrations of celecoxib, which is primarily metabolized by the isoenzyme. The possibility of prolonged and/or increased pharmacologic effects of celecoxib should be considered.
MANAGEMENT: Clinical monitoring for altered effects of celecoxib is recommended following initiation or discontinuation of a CYP450 2C9 inhibitor. Dosage adjustments may be required if an interaction is suspected. Patients should be advised to notify their physician if they experience potential signs and symptoms of celecoxib toxicity such as abdominal pain, black or tarry stools, nausea, vomiting, lethargy, fluid retention, swelling of legs, and worsening heart failure.
- "Product Information. Celebrex (celecoxib)." Searle, Chicago, IL.
Generic Name: celecoxib
Brand name: Celebrex, Celebrex
Synonyms: Celecoxib
Generic Name: fluvoxamine
Brand name: Luvox, Luvox CR
Synonyms: Fluvoxamine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Celexib 100- EZS-Fluvoxamine Maleate
- Celexib 100- EZS-Fluvoxamine Tablets
- Celexib 100- EZS-Fluxid
- Celexib 100- EZS-Fluzone
- Celexib 100- EZS-Fluzone 2013-2014 Formula
- Celexib 100- EZS-Fluzone 2015-2016 Formula
- Fluvoxamine Extended-Release Capsules-Cellcept
- Fluvoxamine Extended-Release Capsules-CellCept (Mycophenolate Mofetil Capsules)
- Fluvoxamine Extended-Release Capsules-CellCept (Mycophenolate Mofetil Injection Solution)
- Fluvoxamine Extended-Release Capsules-CellCept (Mycophenolate Mofetil Oral Suspension)
- Fluvoxamine Extended-Release Capsules-CellCept (Mycophenolate Mofetil Tablets)
- Fluvoxamine Extended-Release Capsules-Cellcept Oral