About us Contacts Drug interactions: 390 212
Drug search by name

Celexib 100- EZS and Oxycontin

Determining the interaction of Celexib 100- EZS and Oxycontin and the possibility of their joint administration.

Check result:
Celexib 100- EZS <> Oxycontin
Relevance: 12.06.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Celecoxib may increase the blood levels and effects of oxyCODONE. If your doctor does prescribe these medications together, you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience increased side effects or if your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Coadministration with celecoxib may increase the plasma concentrations of drugs that are substrates of the CYP450 2D6 isoenzyme. The mechanism is decreased clearance due to inhibition of CYP450 2D6 activity by celecoxib.

MANAGEMENT: Caution is advised if celecoxib must be used concurrently with medications that undergo metabolism by CYP450 2D6, particularly those with a narrow therapeutic range. Dosage adjustments as well as clinical and laboratory monitoring may be appropriate for some drugs whenever celecoxib is added to or withdrawn from therapy.

References
  • "Product Information. Celebrex (celecoxib)." Searle, Chicago, IL.
Celexib 100- EZS

Generic Name: celecoxib

Brand name: Celebrex, Celebrex

Synonyms: Celecoxib

Oxycontin

Generic Name: oxycodone

Brand name: Oxaydo, Oxycontin, Oxyfast, Roxicodone, Xtampza ER, Oxycontin, Oxecta, Roxybond, Xtampza ER; oxycodone is also present in the following combination drugs: Combunox, Endocet, Endodan, Moxduo, Oxycodan, Percocet, Percodan, Primlev, Roxicet, Xartemis XR, and others, OxyIR, Roxybond

Synonyms: OxyContin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction