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Cellcept and Levaquin (Levofloxacin Oral Solution)

Determining the interaction of Cellcept and Levaquin (Levofloxacin Oral Solution) and the possibility of their joint administration.

Check result:
Cellcept <> Levaquin (Levofloxacin Oral Solution)
Relevance: 15.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

LevoFLOXacin may reduce the blood levels and effects of mycophenolate mofetil. You may need a dose adjustment if you have been taking mycophenolate mofetil and are starting treatment with levoFLOXacin. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

MONITOR: Theoretically, drugs that alter the gastrointestinal flora (e.g., antibiotics) may reduce the oral bioavailability of mycophenolic acid products. Some investigators believe that antimicrobials may interfere with the enterohepatic recirculation of mycophenolic acid by decreasing bacterial hydrolytic enzymes in the gastrointestinal tract that are responsible for regenerating mycophenolic acid from its glucuronide metabolite following first-pass metabolism.

MANAGEMENT: Close clinical and laboratory monitoring for evidence of diminished immunosuppressive effect of mycophenolic acid is recommended during concomitant therapy with anti-infective agents.

References
  • "Product Information. Myfortic (mycophenolic acid)." Novartis Pharmaceuticals, East Hanover, NJ.
  • "Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Cellcept

Generic Name: mycophenolate mofetil

Brand name: Cellcept, Myfortic, MMF

Synonyms: CellCept

Levaquin (Levofloxacin Oral Solution)

Generic Name: levofloxacin

Brand name: Levaquin

Synonyms: Levaquin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle