CellCept (Mycophenolate Mofetil Tablets) and Clindamycin Oral Solution
Determining the interaction of CellCept (Mycophenolate Mofetil Tablets) and Clindamycin Oral Solution and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Clindamycin may reduce the blood levels and effects of mycophenolate mofetil. You may need a dose adjustment if you have been taking mycophenolate mofetil and are starting treatment with clindamycin. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Theoretically, drugs that alter the gastrointestinal flora (e.g., antibiotics) may reduce the oral bioavailability of mycophenolic acid products. Some investigators believe that antimicrobials may interfere with the enterohepatic recirculation of mycophenolic acid by decreasing bacterial hydrolytic enzymes in the gastrointestinal tract that are responsible for regenerating mycophenolic acid from its glucuronide metabolite following first-pass metabolism.
MANAGEMENT: Close clinical and laboratory monitoring for evidence of diminished immunosuppressive effect of mycophenolic acid is recommended during concomitant therapy with anti-infective agents.
- "Product Information. Myfortic (mycophenolic acid)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. CellCept (mycophenolate mofetil)." Roche Laboratories, Nutley, NJ.
Generic Name: mycophenolate mofetil
Brand name: Cellcept, Myfortic, MMF
Synonyms: CellCept
Generic Name: clindamycin
Brand name: Cleocin HCl, Cleocin Pediatric, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage, Clindesse, ClindaMax Vaginal, Cleocin
Synonyms: Clindamycin, Clindamycin (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Oral, Injection, Intravenous
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Palmitate Hydrochloride Granules
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Phosphate
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Phosphate and Benzoyl Peroxide
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Phosphate topical
- CellCept (Mycophenolate Mofetil Tablets)-Clindamycin Pledget
- Clindamycin Oral Solution-Cellcept Oral
- Clindamycin Oral Solution-Celontin
- Clindamycin Oral Solution-Celontin Kapseals
- Clindamycin Oral Solution-Cemill
- Clindamycin Oral Solution-Cemill 1000
- Clindamycin Oral Solution-Cemill 500