Certolizumab Vials and Rilonacept Subcutaneous
Determining the interaction of Certolizumab Vials and Rilonacept Subcutaneous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using certolizumab together with rilonacept is not recommended. Combining these medications can increase the risk of serious infections. Contact your doctor immediately if you experience fever, chills, body aches, sore throat, muscle weakness, or other flu-like symptoms during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:GENERALLY AVOID: The use of an interleukin-1 (IL-1) blocker in combination with a tumor necrosis factor (TNF) blocker may increase the risk of neutropenia and serious infections, possibly due to additive immunosuppressive effects. In a clinical study, neutropenia occurred in 3% and serious infections in 7% of patients receiving the IL-1 blocker anakinra in combination with a TNF blocker (n=58). No added benefit has been observed with the combination relative to either agent alone.
MANAGEMENT: Concomitant use of an IL-1 blocker and a TNF blocker is not recommended.
- "Product Information. Arcalyst (rilonacept)." Regeneron Pharmaceuticals Inc, Tarrytown, NY.
- "Product Information. Simponi (golimumab)." Centocor Inc, Malvern, PA.
- Pharmaceutical Society of Australia "APPGuide online. Australian prescription products guide online. Available from: URL: http://www.appco.com.au/appguide/default.asp." ([2006]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Cimzia (certolizumab)." UCB Pharma Inc, Smyrna, GA.
- Cerner Multum, Inc. "Australian Product Information." O 0
- "Product Information. Ilaris (canakinumab)." Novartis Pharmaceuticals, East Hanover, NJ.
- "Product Information. Kineret (anakinra)." Amgen, Thousand Oaks, CA.
Generic Name: certolizumab
Brand name: Cimzia, Cimzia Starter
Synonyms: Certolizumab, Certolizumab Pegol
Generic Name: rilonacept
Brand name: Arcalyst
Synonyms: Rilonacept
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Certolizumab Vials-Rilpivirine
- Certolizumab Vials-Rilpivirine Hydrochloride
- Certolizumab Vials-Rilutek
- Certolizumab Vials-Riluzole
- Certolizumab Vials-Riluzole Suspension
- Certolizumab Vials-Riluzole Tablets
- Rilonacept Subcutaneous-Cerubidine
- Rilonacept Subcutaneous-Cervarix
- Rilonacept Subcutaneous-Cervarix Intramuscular
- Rilonacept Subcutaneous-Cervidil
- Rilonacept Subcutaneous-Cesamet
- Rilonacept Subcutaneous-Cesia