Cevimeline and Methadone Oral Concentrate
Determining the interaction of Cevimeline and Methadone Oral Concentrate and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Methadone may increase the blood levels of cevimeline. This can increase side effects such as nausea, vomiting, diarrhea, sweating, drooling, increased urination, blurred vision, confusion, tremor, heart palpitations, and irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inhibitors of CYP450 2D6 and/or 3A4 may increase the plasma concentrations of cevimeline, which is metabolized by these isoenzymes.
MANAGEMENT: Dosage adjustments and clinical monitoring may be appropriate whenever a CYP450 2D6 and/or 3A4 inhibitor is added to or withdrawn from therapy. Patients should be advised to notify their physician if they experience excessive adverse cholinergic effects of cevimeline such as nausea, vomiting, diarrhea, sweating, salivation, urinary frequency, visual disturbance, confusion, tremor, palpitations, or irregular heartbeat.
- "Product Information. Evoxac (cevimeline)" Daiichi Pharmaceuticals, Fort lee, NJ.
Generic Name: methadone
Brand name: Dolophine, Methadose, Methadose Sugar-Free, Diskets
Synonyms: Methadone
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cevimeline-Methadone Oral Solution
- Cevimeline-Methadone Powder
- Cevimeline-Methadone Solution
- Cevimeline-Methadone Tablets
- Cevimeline-Methadone Tablets for Oral Suspension
- Cevimeline-Methadose
- Methadone Oral Concentrate-Cevimeline Hydrochloride
- Methadone Oral Concentrate-Chamomile
- Methadone Oral Concentrate-Chantix
- Methadone Oral Concentrate-Chantix Continuing Month Pak
- Methadone Oral Concentrate-Chantix Start Month Pak
- Methadone Oral Concentrate-Chantix Starter Pack