Cevimeline Hydrochloride and Doxepin Tablets
Determining the interaction of Cevimeline Hydrochloride and Doxepin Tablets and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Doxepin may increase the blood levels of cevimeline. This can increase side effects such as nausea, vomiting, diarrhea, sweating, drooling, increased urination, blurred vision, confusion, tremor, heart palpitations, and irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Coadministration with inhibitors of CYP450 2D6 and/or 3A4 may increase the plasma concentrations of cevimeline, which is metabolized by these isoenzymes.
MANAGEMENT: Dosage adjustments and clinical monitoring may be appropriate whenever a CYP450 2D6 and/or 3A4 inhibitor is added to or withdrawn from therapy. Patients should be advised to notify their physician if they experience excessive adverse cholinergic effects of cevimeline such as nausea, vomiting, diarrhea, sweating, salivation, urinary frequency, visual disturbance, confusion, tremor, palpitations, or irregular heartbeat.
- "Product Information. Evoxac (cevimeline)" Daiichi Pharmaceuticals, Fort lee, NJ.
Generic Name: cevimeline
Brand name: Evoxac
Synonyms: Cevimeline
Generic Name: doxepin
Brand name: Silenor, Sinequan, Sinequan
Synonyms: Doxepin (Sinequan), Doxepin (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cevimeline Hydrochloride-Doxepin topical
- Cevimeline Hydrochloride-Doxercalciferol
- Cevimeline Hydrochloride-Doxercalciferol Capsules
- Cevimeline Hydrochloride-Doxercalciferol Injection
- Cevimeline Hydrochloride-Doxercalciferol oral/injection
- Cevimeline Hydrochloride-Doxil
- Doxepin Tablets-Chamomile
- Doxepin Tablets-Chantix
- Doxepin Tablets-Chantix Continuing Month Pak
- Doxepin Tablets-Chantix Start Month Pak
- Doxepin Tablets-Chantix Starter Pack
- Doxepin Tablets-Chantix Starting Month Box