Cevimeline Hydrochloride and Zykadia
Determining the interaction of Cevimeline Hydrochloride and Zykadia and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.MONITOR: Coadministration with inhibitors of CYP450 2D6 and/or 3A4 may increase the plasma concentrations of cevimeline, which is metabolized by these isoenzymes. MANAGEMENT: Dosage adjustments and clinical monitoring may be appropriate whenever a CYP450 2D6 and/or 3A4 inhibitor is added to or withdrawn from therapy. Patients should be advised to notify their physician if they experience excessive adverse cholinergic effects of cevimeline such as nausea, vomiting, diarrhea, sweating, salivation, urinary frequency, visual disturbance, confusion, tremor, palpitations, or irregular heartbeat. References "Product Information. Evoxac (cevimeline)" Daiichi Pharmaceuticals, Fort lee, NJ.
Professional:MONITOR: Coadministration with inhibitors of CYP450 2D6 and/or 3A4 may increase the plasma concentrations of cevimeline, which is metabolized by these isoenzymes.
MANAGEMENT: Dosage adjustments and clinical monitoring may be appropriate whenever a CYP450 2D6 and/or 3A4 inhibitor is added to or withdrawn from therapy. Patients should be advised to notify their physician if they experience excessive adverse cholinergic effects of cevimeline such as nausea, vomiting, diarrhea, sweating, salivation, urinary frequency, visual disturbance, confusion, tremor, palpitations, or irregular heartbeat.
- "Product Information. Evoxac (cevimeline)" Daiichi Pharmaceuticals, Fort lee, NJ.
Generic Name: cevimeline
Brand name: Evoxac
Synonyms: Cevimeline
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cevimeline Hydrochloride-Zylet
- Cevimeline Hydrochloride-Zylet ophthalmic
- Cevimeline Hydrochloride-Zyloprim
- Cevimeline Hydrochloride-Zymine Liquid
- Cevimeline Hydrochloride-Zymine-D
- Cevimeline Hydrochloride-Zyncof
- Zykadia-Chamomile
- Zykadia-Chantix
- Zykadia-Chantix Continuing Month Pak
- Zykadia-Chantix Start Month Pak
- Zykadia-Chantix Starter Pack
- Zykadia-Chantix Starting Month Box