Chenodal and Estrace (Estradiol Vaginal Cream)
Determining the interaction of Chenodal and Estrace (Estradiol Vaginal Cream) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Talk to your doctor before using chenodeoxycholic acid together with estradiol topical. Prolonged use of estradiol topical can increase the risk for cholesterol gallstones and counteract the effectiveness of chenodeoxycholic acid in dissolving the stones. Your doctor may be able to suggest safer alternatives to estradiol topical while you are being treated with chenodeoxycholic acid. Otherwise, you may require more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Drugs like estrogens, oral contraceptives, fibrates, and possibly other lipid-lowering agents that increase biliary cholesterol secretion may potentiate the risk of cholesterol gallstones and counteract the effectiveness of chenodeoxycholic acid.
MANAGEMENT: Therapeutic effects of chenodeoxycholic acid should be closely monitored if concomitant use with estrogens, oral contraceptives, fibrates, and certain other lipid-lowering agents cannot be avoided.
- "Product Information. Chenodal (chenodeoxycholic acid)." Manchester Pharmaceutical, Fort Collins, CO.
Generic Name: estradiol topical
Brand name: Estrace Vaginal, Estring, Vagifem, Yuvafem, Imvexxy
Synonyms: Estrace Vaginal (local), Estrace Cream
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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