Chenodiol and Welchol

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Taking the chenodeoxycholic acid and colesevelam doses too close together may interfere with the absorption of chenodeoxycholic acid and reduce its effectiveness. To prevent or minimize the interaction, chenodeoxycholic acid should be taken at least four hours before the colesevelam dose. Contact your doctor if your condition worsens. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

ADJUST DOSING INTERVAL: Bile acid sequestering agents may bind to and decrease the gastrointestinal absorption of chenodeoxycholic acid, which is a naturally occurring human bile acid.

MANAGEMENT: As with other drugs whose absorption may be reduced by bile acid sequestering agents, chenodeoxycholic acid should be administered at least 4 hours before the bile acid sequestering agent. However, adjusting the dosing interval may not completely prevent the interaction.

Chenodiol

Generic Name: chenodeoxycholic acid

Brand name: Chenodal

Synonyms: n.a.

What is Chenodiol?

Welchol

Generic Name: colesevelam

Brand name: Welchol, Colesevelam Hydrochloride

Synonyms: n.a.

What is Welchol?