Children’s Tylenol Plus and Leader Acid Control
Determining the interaction of Children’s Tylenol Plus and Leader Acid Control and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Animal studies have suggested that ranitidine may potentiate the hepatotoxicity of acetaminophen, however, a double-blind placebo-controlled crossover study has failed to confirm this finding in humans. Acetaminophen dosage adjustments are not indicated.
- Rogers SA, Gale KC, Newton JF, et al "Inhibition by ranitidine of acetaminophen conjugation and its possible role in ranitidine potentiation of acetaminophen-induced hepatotoxicity." J Pharmacol Exp Ther 245 (1988): 887-94
- Jack D, Thomas M, Skidmore IF "Ranitidine and paracetamol metabolism." Lancet 2 (1985): 1067
Generic Name: acetaminophen / dextromethorphan
Brand name: Children's Triacting, Triaminic Cough & Sore Throat, Triaminic Cough & Sore Throat Softchews, Tylenol Childrens Plus Cough & Sore Throat, Tylenol Cough, Drixoral Cough/Sore Throat, Tylenol Cough and Sore Throat Daytime, Children's Tylenol Cold + Cough + Sore Throat, Children's Triaminic Cough and Sore Throat, Childrenâs Tylenol Plus, Triaminic Cough/Sore Throat, Tylenol Cough/Sore Throat
Synonyms: Acetaminophen and dextromethorphan
Generic Name: ranitidine
Brand name: Zantac
Synonyms: Ranitidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Children’s Tylenol Plus-Leader Acid Reducer Maximum Strength
- Children’s Tylenol Plus-Leader All Day Allergy
- Children’s Tylenol Plus-Leader Allergy D 12
- Children’s Tylenol Plus-Leader Allergy Relief
- Children’s Tylenol Plus-Leader Allergy Relief D-24
- Children’s Tylenol Plus-Leader Allerhist
- Leader Acid Control-ChiRhoStim
- Leader Acid Control-Chlo Hist
- Leader Acid Control-Chlo Tuss (Chlophedianol/Dexbrompheniramine/Phenylephrine Liquid)
- Leader Acid Control-Chlo Tuss (Pseudoephedrine, Dexbrompheniramine, and Chlophedianol Liquid)
- Leader Acid Control-Chlo Tuss EX
- Leader Acid Control-Chlo-Amine