Chloramphenicol and Combivir
Determining the interaction of Chloramphenicol and Combivir and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Chloramphenicol has been shown to inhibit the glucuronidation of zidovudine in vitro. However, a clinically significant interaction has not been demonstrated.
- Sim SM, Back DJ, Breckenridge AM "The effect of various drugs on the glucuronidation of zidovudine (azidothymidine; AZT) by human liver microsomes." Br J Clin Pharmacol 32 (1991): 17-21
- Burger DM, Meenhorst PL, Koks CH, Beijnen JH "Drug interactions with zidovudine." AIDS 7 (1993): 445-60
Generic Name: chloramphenicol
Brand name:
Synonyms: Chloramphenicol (Systemic)
Generic Name: lamivudine / zidovudine
Brand name: Combivir
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Chloramphenicol-Combunox
- Chloramphenicol-Cometriq
- Chloramphenicol-Comfort Pac w/Tizanidine
- Chloramphenicol-Comfort Pac with Cyclobenzaprine
- Chloramphenicol-Comfrey
- Chloramphenicol-Commit
- Combivir-Chloramphenicol (Systemic)
- Combivir-Chloramphenicol Injection
- Combivir-Chloramphenicol Ophthalmic
- Combivir-Chloramphenicol Oral, Intravenous, Injection
- Combivir-Chloramphenicol Otic
- Combivir-Chloramphenicol Sodium Succinate