Chloramphenicol Injection and Kaletra

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Coadministration with inhibitors of CYP450 3A4 may increase the plasma concentrations of lopinavir, which is primarily metabolized by the isoenzyme. The magnitude and clinical significance of this interaction are unknown, particularly when in the presence of ritonavir as a pharmacokinetic booster. Limited data indicate that ketoconazole, a potent CYP450 3A4 inhibitor, does not substantially alter the plasma concentrations of lopinavir administered as lopinavir-ritonavir in a 4:1 ratio.

Chloramphenicol Injection

Generic Name: chloramphenicol

Brand name:

Synonyms: Chloramphenicol, Chloramphenicol (Systemic)

What is Chloramphenicol Injection?

Kaletra

Generic Name: lopinavir / ritonavir

Brand name: Kaletra

Synonyms: n.a.

What is Kaletra?