Chlorcyclizine and phenylephrine and Pitolisant Hydrochloride
Determining the interaction of Chlorcyclizine and phenylephrine and Pitolisant Hydrochloride and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this interaction is not currently available.GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant. MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided. References Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0 "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Professional:GENERALLY AVOID: Because pitolisant enhances the activity of histaminergic neurons in the brain, centrally acting histamine H1-receptor antagonists or medicines with H1-receptor antagonist properties (e.g., tri- and tetracyclic antidepressants) may impair the efficacy of pitolisant.
MANAGEMENT: According to the manufacturer, coadministration of pitolisant with centrally acting H1-receptor antagonists or tri- and tetracyclic antidepressants should be avoided.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
- "Product Information. Wakix (pitolisant)." Harmony Biosciences, LLC, Plymouth Meeting, PA.
Generic Name: chlorcyclizine / phenylephrine
Brand name: Dallergy
Synonyms: n.a.
Generic Name: pitolisant
Brand name: Wakix
Synonyms: Pitolisant
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Chlorcyclizine and phenylephrine-Pitressin
- Chlorcyclizine and phenylephrine-Pitressin Injection
- Chlorcyclizine and phenylephrine-Pitressin Synthetic
- Chlorcyclizine and phenylephrine-Placidyl
- Chlorcyclizine and phenylephrine-Plan B
- Chlorcyclizine and phenylephrine-Plan B One-Step
- Pitolisant Hydrochloride-Chlorcyclizine and pseudoephedrine
- Pitolisant Hydrochloride-Chlorcyclizine and Pseudoephedrine Liquid
- Pitolisant Hydrochloride-Chlorcyclizine and Pseudoephedrine Tablets
- Pitolisant Hydrochloride-Chlordiazepoxide
- Pitolisant Hydrochloride-Chlordiazepoxide and amitriptyline
- Pitolisant Hydrochloride-Chlordiazepoxide and clidinium