Chlordiazepoxide and amitriptyline and Xylocaine HCl
Determining the interaction of Chlordiazepoxide and amitriptyline and Xylocaine HCl and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using chlordiazePOXIDE together with lidocaine can increase nervous system side effects such as dizziness, drowsiness, and confusion. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until the effects of these medications have worn off. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Professional:MONITOR: The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.
MANAGEMENT: Caution is advised during concurrent use. Patients should be monitored for potentially excessive or prolonged CNS depression and other CNS adverse effects. Dosage adjustments may be required.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: amitriptyline / chlordiazepoxide
Brand name: Limbitrol, Limbitrol DS
Synonyms: Amitriptyline and chlordiazepoxide, Amitriptyline and Chlordiazepoxide
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Chlordiazepoxide and amitriptyline-Xylocaine Jelly
- Chlordiazepoxide and amitriptyline-Xylocaine MPF
- Chlordiazepoxide and amitriptyline-Xylocaine MPF With Epinephrine
- Chlordiazepoxide and amitriptyline-Xylocaine Topical application
- Chlordiazepoxide and amitriptyline-Xylocaine Topical Solution
- Chlordiazepoxide and amitriptyline-Xylocaine With Epinephrine
- Xylocaine HCl-Chlordiazepoxide and clidinium
- Xylocaine HCl-Chlordiazepoxide and Clidinium Capsules
- Xylocaine HCl-Chlordiazepoxide Capsules
- Xylocaine HCl-Chlordiazepoxide hydrochloride
- Xylocaine HCl-Chlorex A
- Xylocaine HCl-Chlorex-A 12