Chlordiazepoxide and clidinium and Osimertinib Mesylate

• Generic Name: chlordiazepoxide / clidinium
• Dosage Forms: capsule, gelatin coated
• Other Brand Names: Librax, Clindex, Chlordinium

Chlordiazepoxide is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Chlordiazepoxide affects chemicals in the brain that may be unbalanced.

Clidinium reduces stomach acid and decreases intestinal spasms.

Chlordiazepoxide and clidinium is a combination medicine that may be effective in treating stomach ulcers, irritable bowel syndrome, or symptoms related to intestinal infection. Chlordiazepoxide and clidinium is given together with other medications to treat these conditions. The U.S. Food and Drug Administration has determined that chlordiazepoxide and clidinium is "possibly" effective in treating these conditions.

Chlordiazepoxide and clidinium may also be used for purposes not listed in this medication guide.

• Generic Name: osimertinib
• Dosage Forms: n.a.
• Other Brand Names: Tagrisso

First-line treatment of metastatic NSCLC in patients with epidermal growth factor receptor (EGFR) exon 19 deletions (del19) or exon 21 (L858R) substitution mutations (as detected by an FDA-approved diagnostic test).

Treatment of metastatic NSCLC in patients with EGFR T790M mutation (as detected by an FDA-approved diagnostic test) who have experienced disease progression during or after EGFR tyrosine kinase inhibitor therapy.

Designated an orphan drug by FDA for treatment of EGFR mutation-positive NSCLC.