Chlordiazepoxide hydrochloride and Lidocaine Hydrochloride (Local)
Determining the interaction of Chlordiazepoxide hydrochloride and Lidocaine Hydrochloride (Local) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using chlordiazePOXIDE together with lidocaine can increase nervous system side effects such as dizziness, drowsiness, and confusion. Avoid activities requiring mental alertness such as driving or operating hazardous machinery until the effects of these medications have worn off. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.
Professional:MONITOR: The concomitant use of local anesthetics and benzodiazepines may have additive CNS-depressant effects. Both types of drugs are CNS depressants.
MANAGEMENT: Caution is advised during concurrent use. Patients should be monitored for potentially excessive or prolonged CNS depression and other CNS adverse effects. Dosage adjustments may be required.
- Cerner Multum, Inc. "Australian Product Information." O 0
- Agencia EspaƱola de Medicamentos y Productos Sanitarios Healthcare "Centro de informaciĆ³n online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: chlordiazepoxide
Brand name: Librium, Libritabs, Poxi, Mitran, Formerly available as Librium
Synonyms: Chlordiazepoxide, ChlordiazePOXIDE
Generic Name: lidocaine
Brand name: UAD Caine, Xylocaine HCl, Xylocaine-MPF, Lidoject 1, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, Anestacaine
Synonyms: Lidocaine injection, Lidocaine (Systemic)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Chlordiazepoxide hydrochloride-Lidocaine injection
- Chlordiazepoxide hydrochloride-Lidocaine Injection Solution (Anesthetic)
- Chlordiazepoxide hydrochloride-Lidocaine Intradermal
- Chlordiazepoxide hydrochloride-Lidocaine Intradermal Injection
- Chlordiazepoxide hydrochloride-Lidocaine IV Solution
- Chlordiazepoxide hydrochloride-Lidocaine Jelly
- Lidocaine Hydrochloride (Local)-Chlorex A
- Lidocaine Hydrochloride (Local)-Chlorex-A 12
- Lidocaine Hydrochloride (Local)-Chloromag
- Lidocaine Hydrochloride (Local)-Chloromag injection
- Lidocaine Hydrochloride (Local)-Chloromycetin
- Lidocaine Hydrochloride (Local)-Chloromycetin Ophthalmic