Chloromycetin Sodium Succinate and Delstrigo
Determining the interaction of Chloromycetin Sodium Succinate and Delstrigo and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with inhibitors of CYP450 3A4 may increase the plasma concentrations of doravirine, which is primarily metabolized by the isoenzyme. In 10 study subjects, administration of a single 50 mg dose of doravirine with the potent CYP450 3A4 inhibitor ritonavir (100 mg twice daily) increased doravirine peak plasma concentration (Cmax), systemic exposure (AUC) and trough plasma concentration (C24hr) by an average of 31%, 254% and 191%, respectively, compared to administration of doravirine alone. When a single 100 mg dose of doravirine was administered with ketoconazole 400 mg once daily in 10 study subjects, doravirine Cmax, AUC and C24hr increased by an average of 25%, 206% and 175%, respectively. These changes are not considered clinically significant.
- "Product Information. Pifeltro (doravirine)." Merck & Company Inc, Whitehouse Station, NJ.
Generic Name: chloramphenicol
Brand name:
Synonyms: n.a.
Generic Name: doravirine / lamivudine / tenofovir
Brand name: Delstrigo
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Chloromycetin Sodium Succinate-Delsym
- Chloromycetin Sodium Succinate-Delsym Adult Night Time Multi-Symptom
- Chloromycetin Sodium Succinate-Delsym Cough Plus Chest Congestion DM
- Chloromycetin Sodium Succinate-Delsym Cough Plus Cold Day Time
- Chloromycetin Sodium Succinate-Delsym Cough Plus Cold Night Time
- Chloromycetin Sodium Succinate-Delsym Cough Relief
- Delstrigo-Chloroprocaine
- Delstrigo-Chloroptic
- Delstrigo-Chloroquine
- Delstrigo-Chloroquine Oral, Intramuscular
- Delstrigo-Chloroquine Phosphate
- Delstrigo-Chlorothiazide