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Chloroquine Oral, Intramuscular and Fabrazyme

Determining the interaction of Chloroquine Oral, Intramuscular and Fabrazyme and the possibility of their joint administration.

Check result:
Chloroquine Oral, Intramuscular <> Fabrazyme
Relevance: 07.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Using chloroquine and agalsidase beta is not recommended. Using these drugs together can alter the levels of agalsidase beta. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

CONTRAINDICATED: Amiodarone, chloroquine, and gentamicin may have the potential to inhibit intracellular alpha-galactosidase activity, thereby reducing the pharmacologic effects of agalsidase alfa and agalsidase beta. Clinical data have not been reported.

MANAGEMENT: Agalsidase should not be coadministered with amiodarone, chloroquine, or gentamicin.

References
  • "Product Information. Replagal (agalsidase alfa)." Transkaryotic Therapies Inc, Cambridge, MA.
Chloroquine Oral, Intramuscular

Generic Name: chloroquine

Brand name: Aralen Phosphate, Aralen Hydrochloride

Synonyms: Chloroquine

Fabrazyme

Generic Name: agalsidase beta

Brand name: Fabrazyme

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle