Chloroquine Oral, Intramuscular and Topamax (Topiramate Sprinkle Capsules)
Determining the interaction of Chloroquine Oral, Intramuscular and Topamax (Topiramate Sprinkle Capsules) and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Chloroquine may make topiramate less effective in treating epilepsy or preventing convulsions or seizures. Talk to your doctor if you have ever had epilepsy, convulsions, or seizures, or if you have any questions or concerns. You may need more frequent monitoring by your doctor to safely use both medicines, or your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Chloroquine may lower the convulsive threshold, which may antagonize the action of antiepileptic medications. Seizures have been rarely reported in patients on chloroquine therapy. The mechanism is unknown.
MANAGEMENT: The potential risks and benefits should be evaluated prior to initiating chloroquine in patients on anticonvulsant therapy. In addition, patients with a history of epilepsy should be advised about the risk of chloroquine-induced seizures. Alternative anti-malarial agents may be required. Local treatment guidelines should be consulted.
- "Product Information. Aralen (chloroquine)." Sanofi Winthrop Pharmaceuticals, New York, NY.
- Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Generic Name: chloroquine
Brand name: Aralen Phosphate, Aralen Hydrochloride
Synonyms: Chloroquine
Generic Name: topiramate
Brand name: Qudexy XR, Topamax, Topamax Sprinkle, Topiragen, Trokendi XR, Qudexy XR Sprinkle
Synonyms: Topamax
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Topamax (Topiramate Sprinkle Capsules)-Chloroquine Phosphate
- Topamax (Topiramate Sprinkle Capsules)-Chlorothiazide
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- Topamax (Topiramate Sprinkle Capsules)-Chlorothiazide Sodium