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Chlorpheniramine, Phenylephrine, and Dextromethorphan and Halothane

Determining the interaction of Chlorpheniramine, Phenylephrine, and Dextromethorphan and Halothane and the possibility of their joint administration.

Check result:

Chlorpheniramine, Phenylephrine, and Dextromethorphan <> Halothane

Relevance: 12.07.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Before you undergo any procedure where halothane may be used, let your doctor know if you are currently using phenylephrine. Combining these medications may cause irregular heart rhythm. You should be closely monitored by the doctor during the procedure, and the dosage of phenylephrine adjusted as necessary. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

GENERALLY AVOID: The combination of phenylephrine and halothane may increase the risk of ventricular irritability and cardiac arrhythmias. Adverse events have been reported in anesthetized patients after administration of phenylephrine ophthalmic drops.

MANAGEMENT: This combination should be avoided or used very cautiously and the patient's hemodynamic status should be closely monitored.

References

"Product Information. Neo-Synephrine (phenylephrine)." Abbott Pharmaceutical, Abbott Park, IL.
Agencia Española de Medicamentos y Productos Sanitarios Healthcare "Centro de información online de medicamentos de la AEMPS - CIMA. Available from: URL: https://cima.aemps.es/cima/publico/home.html." ([2018]):
Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

Chlorpheniramine, Phenylephrine, and Dextromethorphan

Generic Name: chlorpheniramine / dextromethorphan / phenylephrine

Brand name: Alka-Seltzer Plus Cold and Cough, Balamine DM, Ed A-Hist DM, Gencontuss, Giltuss Allergy Plus, NoHist DM, Robitussin Cough & Allergy, Cerose DM, Tussar DM, Liquituss R-DM, Atuss DM, Norel DM, Poly-Tussin DM, De-Chlor DM, De-Chlor DR, Coldtuss-DR, Tri-Vent DPC, Atuss DR, Corfen-DM, Uni-Tuss DM, Mintuss DR, Trital DM, P Chlor DM, Dex PC, Rondec-DM Drops, Rondec-DM, Donatussin DM Drops, Ceron-DM Drops, Ceron-DM, Rondex-DM, Rondex-DM Drops, Dec-Chlorphen DM, Dec-Chlorphen DM Drops, HistadecDM, CP Dec DM, Neo DM Drops, Cardec DM Drops, Reme Tussin DM, Maxiphen ADT, Tussplex DM, Robitussin Pediatric Cough & Cold Nighttime, Robitussin Cough & Cold Nighttime, Cardec DM, C-Phen DM, C-Phen DM Drops, Sildec-PE DM Drops, Sildec-PE DM, Nasohist-DM, DM-PE-Chlor, CP Dec-DM Drops, PD-Cof Drops, PD-Cof, Zotex-12D, Quartuss DM, Nohist-DMX, Sonahist-DM, Relahist-DM, Z-Dex 12 D, Bronkids, Statuss DM, Albatussin SR, NoHist-PDX, Re DCP, Centergy DM, Zoden DM Drops, Trigofen DM Drops, Nasohist-DM Pediatric, Tri-Dex PE, Virdec DM, Norel CS, EndaCof Drops, Giltuss Children's Allergy Plus, Maxichlor PEH DM

Synonyms: Chlorpheniramine, dextromethorphan, and phenylephrine

What is Chlorpheniramine, Phenylephrine, and Dextromethorphan?

Halothane

Generic Name: halothane

Brand name:

Synonyms: n.a.

What is Halothane?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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