Chlorpheniramine, phenylephrine, and phenyltoloxamine and Indinavir Sulfate

• Generic Name: chlorpheniramine / phenylephrine / phenyltoloxamine
• Dosage Forms: n.a.
• Other Brand Names: Chlorex A, Nalex-A, NoHist-A, West-Decon M, Comhist, Comhist LA, Q-Hist LA, Chlortox, Linhist-LA, C-Hist-SR, Nalex-A SR, Coldex, Rhinacon A

Chlorpheniramine and phenyltoloxamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, phenylephrine, and phenyltoloxamine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

chlorpheniramine, phenylephrine, and phenyltoloxamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, phenylephrine, and phenyltoloxamine may also be used for purposes not listed in this medication guide.

• Generic Name: indinavir
• Dosage Forms: n.a.
• Other Brand Names: Crixivan

Treatment of HIV infection in adults, adolescents, and pediatric patients; used in conjunction with other antiretrovirals.

Experts state indinavir not recommended for initial treatment regimens in antiretroviral-naive adults and adolescents because of inconvenient dosing regimen, fluid requirements, and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir with low-dose ritonavir (ritonavir-boosted indinavir) not recommended for initial therapy in antiretroviral-naive adults and adolescents because of fluid requirements and toxicities (e.g., nephrolithiasis, crystalluria).

Indinavir (with or without low-dose ritonavir) not recommended for initial treatment regimens in antiretroviral-naive pediatric patients because of high incidence of hematuria, sterile leukocyturia, and nephrolithiasis in children.