Chlorpheniramine, phenylephrine, and phenyltoloxamine and Mipomersen Sodium

• Generic Name: chlorpheniramine / phenylephrine / phenyltoloxamine
• Dosage Forms: n.a.
• Other Brand Names: Chlorex A, Nalex-A, NoHist-A, West-Decon M, Comhist, Comhist LA, Q-Hist LA, Chlortox, Linhist-LA, C-Hist-SR, Nalex-A SR, Coldex, Rhinacon A

Chlorpheniramine and phenyltoloxamine are antihistamines that reduce the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Chlorpheniramine, phenylephrine, and phenyltoloxamine is a combination medicine used to treat cough, runny or stuffy nose, sneezing, itching, and watery eyes caused by allergies, the common cold, or the flu.

chlorpheniramine, phenylephrine, and phenyltoloxamine will not treat a cough that is caused by smoking, asthma, or emphysema.

Chlorpheniramine, phenylephrine, and phenyltoloxamine may also be used for purposes not listed in this medication guide.

• Generic Name: mipomersen
• Dosage Forms: n.a.
• Other Brand Names: Kynamro

Adjunct to other antilipemic agents and diet to reduce LDL-cholesterol, apolipoprotein B (apo B), total cholesterol, and non-HDL-cholesterol concentrations in the management of homozygous familial hypercholesterolemia (designated an orphan drug by US FDA for use in this condition).

Safety and efficacy not established in patients with hypercholesterolemia who do not have homozygous familial hypercholesterolemia.

Safety and efficacy as an adjunct to LDL apheresis not established; use in combination with LDL apheresis not recommended.

Effects on cardiovascular morbidity and mortality not established.