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Cholbam and Welchol

Determining the interaction of Cholbam and Welchol and the possibility of their joint administration.

Check result:

Cholbam <> Welchol

Relevance: 02.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Colesevelam may interfere with the absorption of cholic acid and reduce its effectiveness in treating your condition. You should take cholic acid at least 1 hour before or 4 to 6 hours (or at as great an interval as possible) after colesevelam. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medication without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: Bile acid binding resins can adsorb bile acids and may reduce the bioavailability of cholic acid. Aluminum-based antacids have been shown to adsorb bile acids in vitro and may interact similarly.

MANAGEMENT: Cholic acid should be taken at least 1 hour before or 4 to 6 hours (or at as great an interval as possible) after a bile acid binding resin or aluminum-based antacid.

References

"Product Information. Cholbam (cholic acid)." Manchester Pharmaceutical, Fort Collins, CO.

Cholbam

Generic Name: cholic acid

Brand name: Cholbam

Synonyms: n.a.

What is Cholbam?

Welchol

Generic Name: colesevelam

Brand name: Welchol, Colesevelam Hydrochloride

Synonyms: n.a.

What is Welchol?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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