Choledyl Expectorant Elixir and Nifedical XL
Determining the interaction of Choledyl Expectorant Elixir and Nifedical XL and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Limited and controversial data suggest the following: either there is no significant interaction between theophylline and dihydropyridine calcium channel blockers, or theophylline serum levels increase after the addition of dihydropyridine calcium channel blockers. Data are available for nifedipine. Theophylline dosage should be reduced if necessary, and plasma levels should be checked when clinically necessary and appropriate. Patients should be advised to report any signs of theophylline toxicity including nausea, vomiting, diarrhea, headache, restlessness, insomnia, or irregular heartbeat to their physician.
- Parrillo SJ, Venditto M "Elevated theophylline blood levels from institution of nifedipine therapy." Ann Emerg Med 13 (1984): 216-7
- Harrod CS "Theophylline toxicity and nifedipine." Ann Intern Med 106 (1987): 480
- Upton RA "Pharmacokinetic interactions between theophylline and other medication (Part II)." Clin Pharmacokinet 20 (1991): 135-50
Generic Name: guaifenesin / oxtriphylline
Brand name:
Synonyms: Oxtriphylline and guaifenesin (Oral)
Generic Name: nifedipine
Brand name: Adalat CC, Afeditab CR, Nifediac CC, Nifedical XL, Procardia, Procardia XL, Adalat
Synonyms: Nifedical XL (Oral)
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Choledyl Expectorant Elixir-Nifedipine
- Choledyl Expectorant Elixir-Nifedipine Capsules
- Choledyl Expectorant Elixir-Nifedipine Extended-Release Tablets
- Choledyl Expectorant Elixir-Niferex
- Choledyl Expectorant Elixir-Niferex Elixir
- Choledyl Expectorant Elixir-Night Cast R Topical
- Nifedical XL-Cholera vaccine
- Nifedical XL-Cholera Vaccine Live Oral
- Nifedical XL-Cholestyramine
- Nifedical XL-Cholestyramine Light
- Nifedical XL-Cholestyramine Resin
- Nifedical XL-Choletec