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Cholestyramine Light and Sulindac

Determining the interaction of Cholestyramine Light and Sulindac and the possibility of their joint administration.

Check result:

Cholestyramine Light <> Sulindac

Relevance: 11.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Cholestyramine may decrease plasma levels of sulindac and its active metabolite, possibly by interfering with enterohepatic recirculation. Separation of doses by three hours did not prevent the interaction. Patients on concomitant therapy should be monitored for reduced response to sulindac. Dosage adjustments may be required.

References

Malloy MJ, Ravis WR, Pennell AT, Hagan DR, Betagari S, Doshi DH "Influence of cholestyramine resin administration on single dose sulindac pharmacokinetics." Int J Clin Pharmacol Ther 32 (1994): 286-9

Cholestyramine Light

Generic Name: cholestyramine

Brand name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: n.a.

What is Cholestyramine Light?

Sulindac

Generic Name: sulindac

Brand name: Clinoril

Synonyms: n.a.

What is Sulindac?

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In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

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