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Cholestyramine Light and Vancomycin injection

Determining the interaction of Cholestyramine Light and Vancomycin injection and the possibility of their joint administration.

Check result:
Cholestyramine Light <> Vancomycin injection
Relevance: 11.10.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

The following interaction applies only if you are receiving vancomycin orally: cholestyramine may interfere with the absorption of vancomycin when these medications are taken at the same time. This may reduce the blood levels and effects of vancomycin. To prevent or minimize the interaction, vancomycin should be taken at least 1 hour before or 4 to 6 hours after the cholestyramine dose. Contact your doctor if your symptoms worsen or your condition changes during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Professional:

ADJUST DOSING INTERVAL: The concomitant use of oral vancomycin and cholestyramine may antagonize the effects of vancomycin. Cholestyramine binds to vancomycin in the gut.

MANAGEMENT: It is recommended to administer doses of oral vancomycin 1 hour before, or 4 to 6 hours after cholestyramine.

References
  • Cerner Multum, Inc. "Australian Product Information." O 0
  • Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
Cholestyramine Light

Generic Name: cholestyramine

Brand name: Cholestyramine Light, Prevalite, Questran, Questran Light, Locholest, Locholest Light, Questran Light Packets, Prevalite Packets, Questran Packets

Synonyms: n.a.

Vancomycin injection

Generic Name: vancomycin

Brand name: FIRST-Vancomycin, Vancocin HCl Pulvules, First-Vancomycin 25, First-Vancomycin 50, Firvanq, Vancocin, First-Vancomycin 25, First-Vancomycin 50

Synonyms: Vancomycin

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle