Chondroitin, glucosamine, and methylsulfonylmethane MSM and Sertraline Oral Concentrate

• Generic Name: chondroitin / glucosamine / methylsulfonylmethane
• Dosage Forms: n.a.
• Other Brand Names: Glucosamine & Chondroitin with MSM, Glucosamine Chondroitin Advanced, Osteo Bi-Flex Advanced, Osteo Bi-Flex Plus MSM, Glucosamine Chondroitin MSM Complex, Duraflex

Chondroitin is a naturally occurring substance formed of sugar chains. Chondroitin is believed to help the body maintain fluid and flexibility in the joints.

Glucosamine is a naturally occurring substance that is believed to help develop and renew cartilage (the hard connective tissue mainly located on bones near joints in the body), and keep it lubricated for better joint movement and flexibility.

Methylsulfonylmethane (MSM) is a naturally occurring form of sulfur that helps support muscles and tendons in the body.

Chondroitin, glucosamine, and MSM is a combination medicine that has been used in alternative medicine as a possibly effective aid in treating osteoarthritis, muscle damage caused by exercise, and other inflammatory joint disorders.

It is not certain whether chondroitin, glucosamine, and MSM is effective in treating any medical condition. Medicinal use of this product has not been approved by the FDA. This product should not be used in place of medication prescribed for you by your doctor.

Chondroitin, glucosamine, and MSM is often sold as an herbal supplement. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Herbal/health supplements should be purchased from a reliable source to minimize the risk of contamination.

Chondroitin, glucosamine, and MSM may also be used for purposes not listed in this product guide.

• Generic Name: sertraline
• Dosage Forms: oral solution, concentrate
• Other Brand Names: Zoloft

Management of major depressive disorder.

Efficacy in hospital settings not established.

APA states that effectiveness of antidepressants is generally comparable between and within classes of medications, including SSRIs, SNRIs, TCAs, MAOIs, and other antidepressants (e.g., bupropion, mirtazapine, trazodone). Choose antidepressant based mainly on patient preference; nature of prior response to medication; safety, tolerability, and anticipated adverse effects; concurrent psychiatric and medical conditions; and specific properties of the medication (e.g., half-life, actions on CYP450 enzymes, other drug interactions). For most patients, an SSRI, SNRI, mirtazapine, or bupropion is considered optimal. Consult APA’s Practice Guidelines for the Treatment of Patients with Major Depressive Disorder for additional information.

Management of OCD; reduces but does not completely eliminate obsessions and compulsions.

Management of panic disorder with or without agoraphobia.

Management of PTSD; more effective in women than in men.

Not effective for combat- or war-related PTSD.

Management of PMDD; improves symptoms (e.g., depressed mood, premenstrual anger/irritability) and functional impairment (e.g., difficulty in concentrating, lethargy) associated with this disorder.

Efficacy when used in conjunction with oral contraceptives for the treatment of PMDD is unknown.

Management of social phobia (social anxiety disorder).

Has been used in the management of premature ejaculation.

Has been used in the management of vascular headaches with equivocal efficacy.