Cimetidine and Gemifloxacin
Determining the interaction of Cimetidine and Gemifloxacin and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Coadministration with cimetidine has been shown to slightly increase the plasma concentrations of gemifloxacin. According to the product labeling, cimetidine (400 mg four times a day for 7 days) increased the peak plasma concentration (Cmax) and area under the concentration-time curve (AUC) of gemifloxacin (320 mg single dose) by an average of 6% and 10%, respectively. These increases are not considered clinically significant.
- "Product Information. Factive (gemifloxacin)." GeneSoft Inc, San Francisco, CA.
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: n.a.
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Gemifloxacin-Cimetidine Hydrochloride
- Gemifloxacin-Cimetidine Injection
- Gemifloxacin-Cimetidine Oral Solution
- Gemifloxacin-Cimetidine Sodium Chloride
- Gemifloxacin-Cimetidine Tablets
- Gemifloxacin-Cimzia