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Cimetidine and Hivid

Determining the interaction of Cimetidine and Hivid and the possibility of their joint administration.

Check result:
Cimetidine <> Hivid
Relevance: 14.12.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Zalcitabine is no longer on the market in the US. Do not take zalcitabine with any other medication.

Professional:

MONITOR: Single dose cimetidine has been shown to reduce the renal clearance of zalcitabine by 24%. The mechanism has not been described.

MANAGEMENT: Monitor the patient closely for neuropathy, hepatotoxicity or mouth ulcerations and reduce zalcitabine doses as indicated.

References
  • "Product Information. Hivid (zalcitabine)." Roche Laboratories, Nutley, NJ.
Cimetidine

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: n.a.

Hivid

Generic Name: zalcitabine

Brand name:

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction