Cimetidine and Levothyroxine oral/injection
Determining the interaction of Cimetidine and Levothyroxine oral/injection and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Cimetidine may decrease the oral absorption of levothyroxine. The mechanism and clinical significance are unknown. Thyroid status of the patient should be monitored during concurrent therapy. Ranitidine reportedly does not have this effect and may be considered as an alternative if there is evidence of an interaction with cimetidine.
- Jonderko G, Jonderko K, Marcisz C, Kotulska A "Effect of cimetidine and ranitidine on absorption of [125I]levothyroxine administered orally." Acta Pharmacol Sin 13 (1992): 391-4
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: n.a.
Generic Name: levothyroxine
Brand name: Levoxyl, Synthroid, Tirosint, Unithroid, Euthyrox, Levothroid, Tirosint-Sol
Synonyms: Levothyroxine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine-Levothyroxine Sodium
- Cimetidine-Levothyroxine Tablets
- Cimetidine-Levoxyl
- Cimetidine-Levsin
- Cimetidine-Levsin (Hyoscyamine Injection)
- Cimetidine-Levsin (Hyoscyamine Tablets)
- Levothyroxine oral/injection-Cimetidine Hydrochloride
- Levothyroxine oral/injection-Cimetidine Injection
- Levothyroxine oral/injection-Cimetidine Oral Solution
- Levothyroxine oral/injection-Cimetidine Sodium Chloride
- Levothyroxine oral/injection-Cimetidine Tablets
- Levothyroxine oral/injection-Cimzia