Cimetidine Hydrochloride and Triamterene and hydrochlorothiazide
Determining the interaction of Cimetidine Hydrochloride and Triamterene and hydrochlorothiazide and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Cimetidine may inhibit the hepatic metabolism and renal tubular secretion of triamterene, resulting in possible increased side effects of triamterene. Clinically, this is a minor interaction. Management consists of monitoring for side effects of triamterene during coadministration.
- Muirhead MR, Somogyi AA, Rolan PE, Bochner F "Effect of cimetidine on renal and hepatic drug elimination: studies with triamterene." Clin Pharmacol Ther 40 (1986): 400-7
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
Generic Name: hydrochlorothiazide / triamterene
Brand name: Dyazide, Maxzide, Maxzide-25
Synonyms: Hydrochlorothiazide and triamterene, Hydrochlorothiazide and Triamterene
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine Hydrochloride-Triamterene and Hydrochlorothiazide Capsules
- Cimetidine Hydrochloride-Triamterene Capsules
- Cimetidine Hydrochloride-Trianex
- Cimetidine Hydrochloride-Trianex Ointment
- Cimetidine Hydrochloride-Trianide Mild-Cream
- Cimetidine Hydrochloride-Triant-HC
- Triamterene and hydrochlorothiazide-Cimetidine Injection
- Triamterene and hydrochlorothiazide-Cimetidine Oral Solution
- Triamterene and hydrochlorothiazide-Cimetidine Sodium Chloride
- Triamterene and hydrochlorothiazide-Cimetidine Tablets
- Triamterene and hydrochlorothiazide-Cimzia
- Triamterene and hydrochlorothiazide-Cimzia (Certolizumab Prefilled Syringes)