Cimetidine Oral Solution and Quinine
Determining the interaction of Cimetidine Oral Solution and Quinine and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Cimetidine may decrease the clearance and increase the elimination half-life of quinine. The mechanism of this interaction is unknown, but probably involves inhibition of the hepatic metabolism of quinine. If cimetidine is added to a stable quinine regime, the clinician may want to monitor the patient more closely for dose-dependent quinine toxicity. Ranitidine does not appear to affect metabolism of quinine.
- Wanwimolruk S, Sunbhanich M, Pongmarutai M, Patamasucon P "Effects of cimetidine and ranitidine on the pharmacokinetics of quinine." Br J Clin Pharmacol 22 (1986): 346-50
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
Generic Name: quinine
Brand name: Qualaquin, QM-260, Quinamm
Synonyms: QuiNINE
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine Oral Solution-Quinine Sulfate
- Cimetidine Oral Solution-Quinine Sulfate Capsules
- Cimetidine Oral Solution-Quinja
- Cimetidine Oral Solution-Quinja Gel
- Cimetidine Oral Solution-Quintabs
- Cimetidine Oral Solution-Quintabs-M
- Quinine-Cimetidine Sodium Chloride
- Quinine-Cimetidine Tablets
- Quinine-Cimzia
- Quinine-Cimzia (Certolizumab Prefilled Syringes)
- Quinine-Cimzia (Certolizumab Vials)
- Quinine-Cinacalcet