Cimetidine Sodium Chloride and Dolasetron Oral, Intravenous
Determining the interaction of Cimetidine Sodium Chloride and Dolasetron Oral, Intravenous and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
Professional:Blood levels of hydrodolasetron, the major active metabolite of dolasetron, were increased 24% when given concomitantly with cimetidine. The mechanism is thought to be inhibition of the metabolism of hydrodolasetron by cimetidine. The clinical significance is unknown but may be low because hydrodolasetron is eliminated by multiple routes. The clinician may consider monitoring the patient more closely for dolasetron toxicity (hypotension, dizziness, arrhythmias) if this combination is used.
- "Product Information. Anzemet (dolasetron)." Hoechst Marion-Roussel Inc, Kansas City, MO.
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
Generic Name: dolasetron
Brand name: Anzemet
Synonyms: Dolasetron
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
- Cimetidine Sodium Chloride-Dolasetron Tablets
- Cimetidine Sodium Chloride-Dolgic LQ Oral
- Cimetidine Sodium Chloride-Dolgic Plus
- Cimetidine Sodium Chloride-Dolobid
- Cimetidine Sodium Chloride-Dologen
- Cimetidine Sodium Chloride-Dologesic
- Dolasetron Oral, Intravenous-Cimetidine Tablets
- Dolasetron Oral, Intravenous-Cimzia
- Dolasetron Oral, Intravenous-Cimzia (Certolizumab Prefilled Syringes)
- Dolasetron Oral, Intravenous-Cimzia (Certolizumab Vials)
- Dolasetron Oral, Intravenous-Cinacalcet
- Dolasetron Oral, Intravenous-Cinacalcet Hydrochloride