Cimetidine Sodium Chloride and Zonalon
Determining the interaction of Cimetidine Sodium Chloride and Zonalon and the possibility of their joint administration.
In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.
Consumer:Using doxepin topical together with cimetidine may increase the effects of doxepin topical. Contact your doctor if you experience increased drowsiness, blurry vision, severe dry mouth, or urinary retention. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Professional:MONITOR: Topical application of doxepin can produce therapeutic concentrations, and drug interactions are therefore possible. Cimetidine may increase serum doxepin concentrations by inhibiting doxepin metabolism. Adverse effects may increase.
MANAGEMENT: Patients should be advised to notify their physician if they experience increased sedation, blurry vision, severe dry mouth, or urinary retention. Ranitidine has not been found to affect serum concentrations of tricyclic antidepressants and may be a better alternative.
- "Product Information. Zonalon (doxepin topical)." Bioglan Pharmaceutical Inc, Malvern, PA.
Generic Name: cimetidine
Brand name: Tagamet HB, Tagamet
Synonyms: Cimetidine
In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.
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- Cimetidine Sodium Chloride-Zontivity
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