Cimetidine Tablets and Cordarone

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Using amiodarone together with cimetidine may increase the effects of amiodarone. Contact your doctor if you experience weakness, slow heart rate, feeling light-headed, or fainting. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MONITOR: Amiodarone serum concentrations may be increased during concomitant therapy with cimetidine and toxicity could result. The mechanism is not known but may involve inhibition of amiodarone hepatic metabolism or of uptake by hepatocytes. Given the long half-life of amiodarone, it may take several weeks for the full effect of the interaction to be realized.

MANAGEMENT: If amiodarone and cimetidine must be used concomitantly, monitoring of amiodarone serum concentrations is recommended.

Cimetidine Tablets

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: Cimetidine

What is Cimetidine Tablets?

Cordarone

Generic Name: amiodarone

Brand name: Cordarone, Pacerone, Nexterone

Synonyms: n.a.

What is Cordarone?