About us Contacts Drug interactions: 390 212
Drug search by name

Cimetidine Tablets and D-3-5

Determining the interaction of Cimetidine Tablets and D-3-5 and the possibility of their joint administration.

Check result:
Cimetidine Tablets <> D-3-5
Relevance: 15.08.2022 Reviewer: Shkutko P.M., M.D., in

In the database of official manuals used in the service creation an interaction registered by statistical results of studies was found, which can either lead to negative consequences for the patient health or strengthen a mutual positive effect. A doctor should be consulted to address the issue of joint drug administration.

Consumer:

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

Professional:

Cimetidine may interfere with the metabolism of vitamin D to its biologically active form. The proposed mechanism is inhibition of hepatic hydroxylation. The clinical significance is unknown. It may be advisable to consider Vitamin D supplementation.

References
  • Odes HS, Fraser GM, Krugliak P, et al "Effect of cimetidine on hepatic vitamin D metabolism in humans." Digestion 46 (1990): 61-4
  • "Product Information. Fosamax Plus D (alendronate-cholecalciferol)." Merck & Company Inc, West Point, PA.
Cimetidine Tablets

Generic Name: cimetidine

Brand name: Tagamet HB, Tagamet

Synonyms: Cimetidine

D-3-5

Generic Name: cholecalciferol

Brand name: D-3-5, D3 Super Strength, D3-50, Decara, Delta D3, D 1000 IU, D3-5, D400, Maximum D3, D2000, Liquid Vitamin D-3, Thera-D 4000, Thera-D Rapid Repletion, D-Vita Drops, Replesta NX, Replesta Children's, Thera-D Sport, D3 1000, Celebrate Vitamin D3 Quick-Melt, Aqueous Vitamin D, Super-Strength D-5000, Super Daily D3, Opurity Vitamin D, VitaJoy Daily D Gummies, D3 Dots, VitaMelts Vitamin D, Replesta

Synonyms: n.a.

In the course of checking the drug compatibility and interactions, data from the following reference sources was used: Drugs.com, Rxlist.com, Webmd.com, Medscape.com.

Interaction with food and lifestyle
Disease interaction